Amr ibn al-As Mosque belongs to the founding story of Fustat in the seventh century, when Egypt gained its first Islamic capital. It began as a place of prayer and community gathering, then underwent repeated enlargement and rebuilding. The institution is much older than most of the fabric standing today.
A broad courtyard and arcaded prayer spaces define the visit. Rather than searching for one celebrated decorative feature, look at the repeated columns and the scale of the gathering space. Its Old Cairo surroundings place that continuing religious role within a much longer urban history.
The best route depends on your starting point. Navigate to Amr ibn al-As Square, Fustat, Old Cairo; for Historic Cairo sites, expect to walk the final part through narrow streets.
A mosque, churches and a synagogue within a few steps of one another: the story of an Egypt where everyone lived side by side. A short, quiet route for a Friday or Saturday morning.